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March 6, 2024 by irrieducation Technology Transfer 0 comments

Fundamentals of Genomic Predictions and Data-Driven Crop Breeding

Course Overview

The course Fundamentals of Genomic Predictions and Data-Driven Crop Breeding offers a thorough exploration of the latest techniques in modern plant breeding. Participants will delve into learning the R language and understanding the basics of quantitative genetics, statistical genomics, and fundamentals of predictive modeling and breeding. The participants will acquire vital knowledge of mixed and advanced models in predictive breeding and their practical applications, giving participants a strong foundation in predictive breeding. The participants will learn and understand when and how to apply genomic selection in breeding programs. The course will also cover G x E interactions in plant breeding and dissecting G x E interactions using predictive breeding and relationship matrices. Attendees will learn about designing training and testing sets, incorporating sparse testing, and more. Additionally, the course covers new concepts like the Usefulness Criterion and Optimal Parental Contributions, aimed at enhancing the effectiveness and efficiency of crossing strategies.

The course features theory and a hands-on approach, allowing participants to work with real-world datasets to implement genomic selection in breeding programs, analyze G x E interactions, and design crossing strategies. This practical experience ensures that participants not only understand theoretical concepts but also develop the essential skills needed to apply genomic selection in their professional endeavors.

Designed for individuals with a basic understanding of crop breeding and genetics, the course is accessible to professionals with varied statistical and R programming expertise, accommodating a diverse audience in the field.

Course Objectives

This course integrates quantitative genetics and statistical genomics with modern breeding approaches, focusing on genomic selection and data-driven decision-making in crop breeding. It enhances understanding of quantitative genetics, statistical models for genomic predictions, and genomic selection implementation in breeding programs. The course covers advanced techniques for parent selection and crossing block design using genotypic and phenotypic datasets. Participants will gain practical skills to apply these concepts in real-world crop improvement scenarios.

By the end of the training course, the participants should be able to:

  • Learn and become familiar with the R language
  • Gain the basic and advanced knowledge of quantitative genetic and statistical genomics relevant to predictive breeding
  • Understand the different relationship matrices and their use in genomic predictions/selections
  • Understand the linear and mixed models to perform phenotypic data analysis and genomic predictions
  • Understand and apply the basic and advanced statistical models to perform the genomic selections
  • Understand the fundamentals of genomic selection (3W’s of Genomic selection: Why, When, and Where to apply it in the breeding program)
  • Understand the G x E interactions and design sparse testing design in dissecting G x E interactions and
  • Understand the Usefulness criterion and Optimal Parental Contributions to design the crossing block and predict the performance of cross combinations.

Target Audience

Plant breeders, geneticists, graduate students, postdoctoral fellows, research scholars, and assistants involved in crop breeding programs. This course is mainly intended for those keen to learn the modern data-driven breeding approaches and how to leverage the data sets to perform genomic selection and implement them in breeding programs.

Key Modules:

  • Module 1: Introduction and Learning R and R Markdown
  • Module 2: Fundamentals of Quantitative Genetics and Predictive Modeling
  • Module 3: G x E Interactions Dissections in Predictive Breeding
  • Module 4:Practical Implementation of Genomic Selection in Plant Breeding
  • Module 5: Breeding and Crossing Scheme Optimizations

Learning Modality

The course will be delivered face-to-face with a mixed modality of synchronous and asynchronous discussions involving theoretical concepts, practical and hands-on exercises, and self-paced e-learning activities.

Course History

This course was initially implemented in 2024 at the International Rice Research Institute (IRRI) Headquarters in Los Baños, Laguna, bringing together around 30 diverse participants from across Asia and Africa to learn about genomic selection and other data-driven strategies in crop breeding (read more here). In the same year, a second implementation was conducted in partnership with the Indian Council of Agricultural Research – Indian Institute of Rice Research (ICAR-IIRR) in Hyderabad, India. This training gathered more than 39 participants from over 20 research institutes, including research scholars, senior research fellows, young professionals, scientists, senior scientists, and assistant professors. The program was highly praised and recognized as one of the most successful courses to date (read more here).

Apply for Fundamentals of Genomic Predictions and Data-Driven Crop Breeding

Course Dates

4-8 August 2025

Deadline of Application

25 June 2025

Course Fee

External participants with accommodation - USD 1,504

The course fee applies to external and non-IRRI participants and includes the training fee, training kit, welcome and closing dinners, daily snacks, minimal meal allowance, medical insurance, airport transfers, and a single-occupancy room at IRRI Dormitory for the duration of the training.

External participants without accommodation - USD 1,292

The course fee applies to external and non-IRRI participants and includes the training fee, training kit, welcome and closing dinners, daily snacks, minimal meal allowance, medical insurance, and airport transfers.

In addition, participants are responsible for covering the cost of their own accommodation.

IRRI Staff - USD 862

The course fee applies to IRRI Staff from both Headquarters and Country Offices and covers the training fee, training kit, welcome and closing dinners, and daily snacks.

In addition, participants are responsible for covering their transportation expenses (including airfare and airport transfers) to and from IRRI HQ, as well as their accommodation and allowance, which should be charged to their respective bus codes.

Click here to apply!

Main Resource Person and Coordinator

Waseem Hussain (Senior Scientist-I, International Rice Research Institute)

Waseem Hussain has diverse research expertise in plant breeding & genetics, quantitative genetics, statistics, and genomics. He has immense experience in providing training to students, scholars, and scientists on quantitative genetics, statistical genomics, and data-driven breeding approaches. Waseem Hussain has trained over 300 crop science scientists and research scholars in quantitative genetics, genomic predictions, and modern data-driven breeding approaches.

In 2023, Waseem Hussain was the coordinator and one of the primary resource persons to provide the training on “Genomic Selections and Modern Data Analysis” to 15 Senior Scientists from the Indian Council of Agricultural Research (ICAR) (https://www.youtube.com/watch?v=wko1b3C07lI). Dr. Hussain is the main person to create the course “Fundamentals of Genomic Predictions and Data-Driven Crop Breeding” in collaboration with IRRI Education.

Grab a chance to connect with Waseem Hussain and learn more about his experiences through Google Scholar and LinkedIn.

Relevant links:

https://whussain2.github.io/teaching/
https://github.com/whussain2/R-for-Plant-Breeding/tree/master/GWAS_in_R
https://github.com/whussain2/ShinyAIM
https://github.com/whussain2/Analysis-pipeline
https://news.irri.org/2022/08/modern-rice-breeding-training-kicks-off.html

Featured Resource Persons

Mahender Anumalla (Scientist I – Breeding Long Duration Rice, International Rice Research Institute, IRRI-South Asia Hub, Hyderabad)

Mahender Anumalla is a Scientist-I for Breeding Long Duration Rice in the late maturity breeding program, IRRI South Asia Hub, Hyderabad. He has extensive research expertise in trait phenotyping, germplasm characterization, base population development for modern breeding, and long-term genetic gain. He has been actively involved in the capacity development program on modern breeding and quantitative genetics to train research scholars, scientists, and students. Mahender Anumalla has explored various mixed models, implemented genomic selection, and performed robust data analysis, mainly for complex traits.

Relevant links:

https://scholar.google.com/citations?user=K3lZDzcAAAAJ&hl=en&oi=ao

https://www.irri.org/about-us/our-people/mahender-anumalla

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